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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUAK1
All Species:
17.27
Human Site:
S532
Identified Species:
29.23
UniProt:
O60285
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60285
NP_055655.1
661
74305
S532
L
K
H
S
S
K
Y
S
A
G
T
M
D
P
A
Chimpanzee
Pan troglodytes
XP_001161041
661
74289
S532
L
K
H
S
S
K
Y
S
A
G
T
M
D
P
A
Rhesus Macaque
Macaca mulatta
XP_001098986
667
74748
S538
L
K
H
S
S
K
Y
S
A
G
A
M
D
P
A
Dog
Lupus familis
XP_538417
666
74288
S537
L
K
H
S
S
K
Y
S
A
G
S
T
D
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q641K5
658
73643
S533
L
K
H
S
S
R
Y
S
D
G
G
T
D
P
A
Rat
Rattus norvegicus
Q66HE5
630
69934
N511
R
K
G
I
L
K
L
N
G
K
F
S
R
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508265
661
73136
A532
L
K
H
S
S
K
Y
A
A
D
G
M
D
S
A
Chicken
Gallus gallus
Q9IA88
798
88848
L524
S
V
A
L
S
S
C
L
A
G
Q
V
M
T
G
Frog
Xenopus laevis
NP_001088596
570
64876
F451
W
A
A
P
H
L
T
F
G
A
L
D
C
P
L
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
G854
L
L
G
E
S
V
M
G
S
Y
N
P
Y
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649991
1427
153426
R1155
T
S
S
N
T
T
T
R
S
G
S
L
S
R
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
I698
V
A
A
N
N
G
G
I
P
S
H
R
D
H
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
K392
S
Q
V
P
V
D
R
K
W
A
L
G
L
Q
S
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
S511
R
W
H
F
G
I
R
S
R
S
Y
P
L
D
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.9
91.7
N.A.
90.9
55.6
N.A.
84.2
26.1
48.5
23.5
N.A.
24.3
N.A.
22.4
N.A.
Protein Similarity:
100
99.8
98
94.4
N.A.
93.8
68
N.A.
88
42.8
61.4
36.2
N.A.
33.6
N.A.
35.8
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
73.3
20
N.A.
73.3
20
6.6
13.3
N.A.
6.6
N.A.
13.3
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
80
26.6
N.A.
80
26.6
6.6
20
N.A.
40
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.1
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.3
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
22
0
0
0
0
8
43
15
8
0
0
0
58
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
8
8
0
8
50
8
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
8
0
0
8
0
0
0
0
% F
% Gly:
0
0
15
0
8
8
8
8
15
50
15
8
0
0
8
% G
% His:
0
0
50
0
8
0
0
0
0
0
8
0
0
8
0
% H
% Ile:
0
0
0
8
0
8
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
50
0
0
0
43
0
8
0
8
0
0
0
0
0
% K
% Leu:
50
8
0
8
8
8
8
8
0
0
15
8
15
8
8
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
29
8
0
0
% M
% Asn:
0
0
0
15
8
0
0
8
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
15
0
0
0
0
8
0
0
15
0
43
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
8
0
0
8
15
% Q
% Arg:
15
0
0
0
0
8
15
8
8
0
0
8
8
8
0
% R
% Ser:
15
8
8
43
58
8
0
43
15
15
15
8
8
8
8
% S
% Thr:
8
0
0
0
8
8
15
0
0
0
15
15
0
15
0
% T
% Val:
8
8
8
0
8
8
0
0
0
0
0
8
0
0
8
% V
% Trp:
8
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
43
0
0
8
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _